How does the outbreak compare to previous ones?
More than 200 people died in an outbreak in Angola from 2004 to 2005 and more than 100 died of the disease in the Democratic Republic of Congo from 1998 to 2000, according to the C.D.C. Other outbreaks of Marburg have not involved as many cases.
In 2021, there was one case in Guinea, which resulted in that person’s death, and three of four people who had the disease in Uganda in 2017 also died, according to the C.D.C.
Experts want to know how the two people contracted the virus in Ghana, said Dr. Francis Kasolo, the W.H.O. representative to the country.
“The current investigation is not only focusing on contacts,” Dr. Kasolo said. “We are also going back to medical records in these areas to see if there were unusual events in terms of cases that presented with symptoms. That is why we are holding back in saying that this is just a one-off event.”
Should we be worried?
The C.D.C.’s office in Ghana is working with local health authorities to assist with testing and epidemiological investigations, said Dr. Jonathan Towner, who leads the Virus Host Ecology Section at the C.D.C.
People in the United States are not at high risk for exposure, Dr. Towner said.
“It’s a very, very low risk probability at this point that there will be some travelers, for example, coming into the country with Marburg right now,” he said.
So far, Dr. Amuasi said, the public health response has been appropriate and transparent. Contacts of the two infected people were monitored, particularly in the 21 days after the two died.